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About Jean A. Frazier

Dr. Jean A. Frazier, M.D., is the Robert M. and Shirley S. Siff Chair in Autism and Professor of Psychiatry and Pediatrics at the University of Massachusetts Medical School. As Co-Director of the Child and Adolescent Neurodevelopment Initiative (CANDI), Dr. Frazier directs a broad research program that addresses a variety of scientific problems relevant to advancing the understanding, diagnosis and treatment of individuals with neurodevelopmental disorders such as early onset bipolar disorder (BPD), schizophrenia and autism. The CANDI team studies all three diagnostic groups since there is often overlap in the clinical symptoms, genetics, and the neuroimaging findings of these disorders and in the clinical interventions used to treat them. Research with each diagnostic group of children informs the work done with the other diagnostic groups. For example, children with autism can have mood dysregulation when asked to shift activities and a significant subset can suffer from a comorbid bipolar disorder or depressive disorder. Children with schizophrenia can also look like they have bipolar disorder with psychotic features and figuring out the diagnostic boundaries can be challenging. By studying all three groups of children, Dr. Frazier hopes to find biomarkers that might be specific to each diagnosis. In addition, she hopes to find biomarkers that may be less specific to diagnosis but more pertinent to disorders of neurodevelopment in general. The overarching goal is for Dr. Frazier's research efforts to lead to improved care of children and families affected by these disorders.

CANDI is involved in a variety of research pursuits including genetic studies, intervention studies and neuroimaging efforts. Dr. Frazier collaborates with a number of investigators both locally and nationally in order to tackle difficult questions. The neuroimaging studies use technologies such as magnetic resonance imaging (MRI) to investigate the development of brain structure and function. Using these techniques Dr. Frazier's team hopes to characterize normal development and advance the understanding of issues surrounding mental illness and atypical development and their interventions.


Present Executive Director, Eunice Kennedy Shriver Center, University of Massachusetts Medical School
Present Faculty appointment, Graduate School of Biomedical Sciences, University of Massachusetts Medical School
Present Co-Director, Child and Adolescent Neurodevelopment Initiative, University of Massachusetts Medical School
Present Vice Chair & Director, Child and Adolescent Psychiatry, University of Massachusetts Medical School
Present Robert M. and Shirley S. Siff Chair in Autism, Professor of Psychiatry and Pediatrics, University of Massachusetts Medical School

Curriculum Vitae


Honors and Awards

  • Top Doctors, U. S. News & World Report (2012)
  • Best Doctors in America (2010-2012)
  • Step up for Kids, Inc. Leadership Award (2007)
  • New England Educational Institute’s Outstanding Educator Award for Mental Health Education (2006)
  • Distinguished Fellow of the American Psychiatric Association (2006)
  • Massachusetts Psychiatric Society-Outstanding Psychiatrist Award for Research (2003)
  • National Alliance For The Mentally Ill- Annual Exemplary Psychiatrist Award (2002)
  • Women in Science and Health Achievement Award, Women's Faculty Committee, UMass Medical School (2016)

Contact Information

University of Massachusetts Medical School
Department of Psychiatry
Biotech One
365 Plantation St., Suite 100
Worcester, MA 01605


Articles (117)