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LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis.
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  • Jay Steingrub, MD, Baystate Health
Document Type
Article, Peer-reviewed
Publication Date
OBJECTIVE: Group IIA secretory phospholipase A2 (sPLA2-IIA), released during inflammation, is increased in severe sepsis, and plasma levels are inversely related to survival. In a previous study, a selective inhibitor of sPLA2-IIA (LY315920NA/S-5920) was
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Citation Information
Crit Care Med 2005 Aug;33(8):1741-8.