"LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis." by Jay Steingrub, MD

Article

LY315920NA/S-5920, a selective inhibitor of group IIA secretory phospholipase A2, fails to improve clinical outcome for patients with severe sepsis.

All Scholarly Works

Jay Steingrub, MD, Baystate Health

Document Type

Article, Peer-reviewed

Publication Date

8-1-2005

Abstract

OBJECTIVE: Group IIA secretory phospholipase A2 (sPLA2-IIA), released during inflammation, is increased in severe sepsis, and plasma levels are inversely related to survival. In a previous study, a selective inhibitor of sPLA2-IIA (LY315920NA/S-5920) was

Publication ISSN

0148-639X

Citation Information

Crit Care Med 2005 Aug;33(8):1741-8.