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Obesity does not alter the pharmacokinetics of drotrecogin alfa (activated) in severe sepsis.
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  • Jay Steingrub, MD, Baystate Health
Document Type
Article, Peer-reviewed
Publication Date
BACKGROUND: Drotrecogin alfa (activated) [DrotAA] is approved for the reduction of mortality in adults with severe sepsis (sepsis with acute organ dysfunction) and high risk of death. Patients whose actual body weight was >135 kg were excluded from the
Publication ISSN
Citation Information
Ann Pharmacother 2005 Feb;39(2):262-7. Epub 2005 Jan 4.