"Obesity does not alter the pharmacokinetics of drotrecogin alfa (activated) in severe sepsis." by Jay Steingrub, MD

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Article

Obesity does not alter the pharmacokinetics of drotrecogin alfa (activated) in severe sepsis.

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Jay Steingrub, MD, Baystate Health

Document Type

Article, Peer-reviewed

Publication Date

2-1-2005

Abstract

BACKGROUND: Drotrecogin alfa (activated) [DrotAA] is approved for the reduction of mortality in adults with severe sepsis (sepsis with acute organ dysfunction) and high risk of death. Patients whose actual body weight was >135 kg were excluded from the

Publication ISSN

1073-449X

Citation Information

Ann Pharmacother 2005 Feb;39(2):262-7. Epub 2005 Jan 4.