A growing body of research has shown that retrieval can enhance future learning of new materials. In the present report, we provide a comprehensive review of the literature on this finding, which we term test-potentiated new learning. Our primary objectives were to (a) produce an integrative review of the existing theoretical explanations, (b) summarize the extant empirical data with a meta-analysis, (c) evaluate the existing accounts with the meta-analytic results, and (d) highlight areas that deserve further investigations. Here, we identified four nonexclusive classes of theoretical accounts, including resource accounts, metacognitive accounts, context accounts, and integration accounts. Our quantitative review of the literature showed that testing reliably potentiates the future learning of new materials by increasing correct recall or by reducing erroneous intrusions, and several factors have a powerful impact on whether testing potentiates or impairs new learning. Results of a metaregression analysis provide considerable support for the integration account. Lastly, we discuss areas of under-investigation and possible directions for future research.