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Selected Works of Jason Shih-Hao Chen
Article
Enantioselective Dichlorination of Allylic Alcohols
Journal of American Chemical Society (2011)
  • K.C. Nicolaou, The Scripps Research Institute
  • Nicholas L. Simmons, The Scripps Research Institute
  • Yongcheng Ying, The Scripps Research Institute
  • Philipp M. Heretsch, The Scripps Research Institute
  • Jason Chen, The Scripps Research Institute
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Abstract
The development of an enantioselective allylic alcohol dichlorination catalyzed by dimeric cinchona alkaloid derivatives and employing aryl iododichlorides as chlorine sources is reported. Reaction optimization, exploration of the substrate scope, and a model for stereoinduction are presented.
Disciplines
Publication Date
2011
DOI
10.1021/ja202555m
Publisher Statement
Reprinted (adapted) with permission from J. Am. Chem. Soc., 2011, 133 (21), pp 8134–8137. Copyright 2011 American Chemical Society.
Citation Information
K.C. Nicolaou, Nicholas L. Simmons, Yongcheng Ying, Philipp M. Heretsch, et al.. "Enantioselective Dichlorination of Allylic Alcohols" Journal of American Chemical Society Vol. 133 Iss. 21 (2011) p. 8134 - 8137
Available at: http://works.bepress.com/jason-shih-hao-chen/6/