Potentials and prospects for application of supercritical fluid technology in bioprocessingProcess Biochem. (1995)
Recent investigations on the application ofsupercritical (SC)Jluid technology in bin- andfood chemistry are reviewed. The gas-antisolvent crystallization and rapid expansion of SC&id emerge as attractive methods for micron-size particle formation. Also gainingground is enzymic catalysis in SC CO,, which offers the possibility of integrated synthesis-product recovery processes. These processes, successfully tested on a lahoratoly scale, need further scale-up and optimization. Supercritical CO, has proven to be unfriendly, or even toxic, for living microorgcmisms, which precludes direct fermentation in dense CO, but does not rule out other useful applications.
Citation InformationA. B. Jarzebski,J. J. Malinowski "Potentials and prospects for application of supercritical fluid technology in bioprocessing" Process Biochem. 30(4) (1995): 343-352.