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Genomic Profiling and In Vitro Analysis of MicroRNAs in Neurodegenerative Disorders
(2009)
Abstract
Genomic profiling and in vitro analysis of microRNAs in neurodegenerative disorders The aims of this proposal were to uncover novel noncoding microRNA-mRNA mechanisms in dementia caused by mutations in the Progranulin gene. We uncovered specific noncoding RNA-mediated pathways in response to Progranulin haploinsufficiency in the frontal cortex of brains from a large cohort of patients.
Disciplines
Publication Date
May 1, 2009
Citation Information
Jannet Kocerha (PI). "Genomic Profiling and In Vitro Analysis of MicroRNAs in Neurodegenerative Disorders," Sponsored by the Mayo Clinic Robert and Clarice Smith Fellowship. (05/01/09- 05/01/2010)