About Jan Kmetko
Jan Kmetko works in the field of biological physics. His research program focuses on addressing issues hindering efforts in structure determination of biological molecules by x-rays, and there are two major bottlenecks. One, some biological molecules are hard or impossible to crystallize, and two, when the crystals are exposed to the intense synchrotron x-ray beam, they often suffer severe radiation damage. Eliminating these two trouble spots would allow the structure of macromolecules to be determined as soon as they are discovered. Experiments aim to address both issues: one, to understand fundamental aspects of crystallizing biological molecules, and two, to learn the physical and chemical mechanisms of radiation damage during x-ray exposure.