Skip to main content
Mediastinal parathyroid adenoma causing primary hyperparathyroidism.
Journal of the Pakistan Medical Association
  • Farhat Abbas, Aga Khan University
  • Syed Raziuddin Biyabani, Aga Khan University
  • Amanullah Memon, Aga Khan University
  • Jamsheer Talati, Aga Khan University
Publication Date
Document Type
Abstract An ectopically placed parathyroid adenoma in the anterior mediastinum is a rare cause of persistent or recurrent primary hyperparathyroidism (PHPT) and is recognized as an important cause of failed primary neck exploration. We encountered 3 such cases amongst 70 surgically treated patients with PHPT (4.3%) over a 20-year period. In 2 cases, the offending adenoma could be removed at first exploration whereas in the 3rd case, it was successfully removed with mediastinal exploration after 2 failed neck explorations. In established cases of PHPT with equivocal preoperative localization studies or negative neck explorations, an ectopically placed parathyroid adenoma should be considered and once localized, should be surgically removed for cure.
Citation Information
Farhat Abbas, Syed Raziuddin Biyabani, Amanullah Memon and Jamsheer Talati. "Mediastinal parathyroid adenoma causing primary hyperparathyroidism." Journal of the Pakistan Medical Association Vol. 57 Iss. 2 (2007) p. 93 - 95
Available at: