Skip to main content
Article
The Interrelations Between Spiritual Well-Being, Pain Interference and Depressive Symptoms in Patients with Multiple Sclerosis
Journal of Behavioral Medicine
  • Sheri A. Nsamenang, McMaster Childrens Hospital
  • Jameson K. Hirsch, East Tennessee State University
  • Raluca Topciu, Barts and the London School of Medicine and Dentistry
  • Andrew D. Goodman, University of Rochester Medical Center
  • Paul R. Duberstein, University of Rochester Medical Center
Document Type
Article
Publication Date
4-1-2016
Description
Depressive symptoms are common in individuals with multiple sclerosis (MS), and are frequently exacerbated by pain; however, spiritual well-being may allow persons with MS to more effectively cope with pain-related deficits in physical and role functioning. We explored the associations between spiritual well-being, pain interference and depressive symptoms, assessing each as a potential mediator, in eighty-one patients being treated for MS, who completed self-report measures: Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being Scale, Pain Effects Scale, and Center for Epidemiologic Studies Depression Scale Revised. At the bivariate level, spiritual well-being and its subscale of meaning and peace were negatively associated with depression and pain interference. In mediation models, depression was not related to pain interference via spiritual well-being, or to spiritual well-being via pain interference. Pain interference was related to depression via spiritual well-being and meaning/peace, and to spiritual well-being and meaning/peace via depressive symptoms. Finally, spiritual well-being and meaning/peace were related to depression via pain interference, and to pain interference via depressive symptoms. For patients with MS, a multi-faceted approach to treatment that includes pain reduction and promotion of spiritual well-being may be beneficial, although amelioration of depression remains a critical task.
Posted Versions
Post-Print
Copyright Statement

This document is an author manuscript from PMC. The final publication is available at Springer via https://doi.org/10.1007/s10865-016-9712-3

Citation Information
Sheri A. Nsamenang, Jameson K. Hirsch, Raluca Topciu, Andrew D. Goodman, et al.. "The Interrelations Between Spiritual Well-Being, Pain Interference and Depressive Symptoms in Patients with Multiple Sclerosis" Journal of Behavioral Medicine Vol. 39 Iss. 2 (2016) p. 355 - 363 ISSN: 1573-3521
Available at: http://works.bepress.com/jameson-hirsch/32/