Article
Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus
Journal of Virology
Document Type
Article
Disciplines
Publication Version
Published Version
Publication Date
7-1-1993
Abstract
Transient expression assays using the reporter gene that encodes chloramphenicol acetyltransferase were used to identify cis-acting sequences necessary for bovine immunodeficiency-like virus (BIV) transactivation. Computer analyses identified two RNA stem-loop structures located immediately downstream of the transcription start site in the long terminal repeat. Deletion analysis of the long terminal repeat indicated that sequences containing the proximal stem-loop structure located between +4 and +31 are required for virus-specific transactivation. Therefore, BIV likely utilizes a mechanism of transactivation similar to that of the human and simian lentiviruses.
Copyright Owner
American Society for Microbiology
Copyright Date
1993
Language
en
File Format
application/pdf
Citation Information
Susan Carpenter, Susan A. Nadin-Davis, Yvonne Wannemuehler and James A. Roth. "Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus" Journal of Virology Vol. 67 Iss. 7 (1993) p. 4399 - 4403 Available at: http://works.bepress.com/james_roth/77/
This article is published as Carpenter, S., S. A. Nadin-Davis, Y. Wannemuehler, and J. A. Roth. "Identification of transactivation-response sequences in the long terminal repeat of bovine immunodeficiency-like virus." Journal of virology 67, no. 7 (1993): 4399-4403. Posted with permission.