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Article
Defective function of leukocytes from cattle persistently infected with bovine viral diarrhea virus, and the influence of recombinant cytokines
American Journal of Veterinary Research
  • Gayle B. Brown, Iowa State University
  • Steve R. Bolin, U.S. Department of Agriculture
  • Dagmar E. Frank, Iowa State University
  • James A. Roth, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
3-1-1991
Abstract

Cattle persistently infected with bovine viral diarrhea (BVD) virus have decreased neutrophil and lymphocyte functions. We reevaluated these functions and further characterized the inhibition of persistent BVD virus infection in neutrophils, using sensitive kinetic assays. In addition, the influence of in vitro incubation of neutrophils with recombinant bovine interferon gamma (~IloIFN gamma) and in vitro incubation of lymphocytes with recombinant bovine interleukin-2 was evaluated.

Comments

This article is published as Brown, G.B., S.R. Bolin, D.E. Frank, and J.A. Roth. 1991. Defective function of leukocytes from cattle persistently infected with bovine viral diarrhea virus, and the influence of recombinant cytokines. Am J Vet Res, 52:381-387.

Rights
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
Language
en
File Format
application/pdf
Citation Information
Gayle B. Brown, Steve R. Bolin, Dagmar E. Frank and James A. Roth. "Defective function of leukocytes from cattle persistently infected with bovine viral diarrhea virus, and the influence of recombinant cytokines" American Journal of Veterinary Research Vol. 52 Iss. 3 (1991) p. 381 - 387
Available at: http://works.bepress.com/james_roth/76/