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Article
Alterations in bovine neutrophil function during the periparturient period
American Journal of Veterinary Research
  • Marcus E. Kehrli, U.S. Department of Agriculture
  • Brian J. Nonnecke, U.S. Department of Agriculture
  • James A. Roth, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
2-1-1989
Abstract

Neutrophils from 8 Holstein heifers were evaluated for function during the periparturient period. Random migration, ingestion of bacteria, superoxide anion production, native (nonenhanced) chemiluminescence, iodination, and antibody-dependent, cell-mediated cytotoxicity by neutrophils were determined. Foremilk samples were evaluated for bacteria. Significant (P < 0.05) increases in random migration of neutrophils, iodination, and chemiluminescence were evident 2 weeks before parturition and then decreased dramatically by the frrst week after parturition. These impairments of neutrophil function after parturition may be manifested as a severe cumulative deficit in the native defenses afforded by the neutrophil.

Comments

This article is published as Kehrli, M.E., B.J. Nonnecke, and J.A. Roth. 1989. Alterations in bovine neutrophil function during the periparturient period. Am J Vet Res, 50:207-214.

Rights
Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted.
Language
en
File Format
application/pdf
Citation Information
Marcus E. Kehrli, Brian J. Nonnecke and James A. Roth. "Alterations in bovine neutrophil function during the periparturient period" American Journal of Veterinary Research Vol. 50 Iss. 2 (1989) p. 207 - 214
Available at: http://works.bepress.com/james_roth/68/