Article
Selective Mating in a Continuous Model of Epistasis
Applied Mathematics and Computation
Document Type
Article
Publication Date
12-1-2005
DOI
10.1016/j.amc.2005.01.059
Disciplines
- Education and
- Mathematics
Abstract
Epistasis is the interaction between two or more genes to control a single phenotype. We model epistasis with a two-locus two-allele problem. The resulting model allows us to examine both population sizes as well as genotypic and phenotypic frequencies. In the context of an example, we show that if epistasis results in an undesirable phenotype, such as a genetically transmitted disease or condition, elimination of undesirable phenotypes from the population through selective breeding may be possible, although such selective breeding could lead to an increase in less desirable phenotypes and possibly the elimination of desirable phenotypes.
Citation Information
James P. Braselton, Martha L. Abell and Lorraine Braselton. "Selective Mating in a Continuous Model of Epistasis" Applied Mathematics and Computation Vol. 171 Iss. 1 (2005) p. 225 - 241 ISSN: 0096-3003 Available at: http://works.bepress.com/james_braselton/45/