|2016 ‐ Present||Assistant Professor, Nova Southeastern University ‐ College of Psychology|
|2006||Ph.D., Neuroscience, Tulane University|
|1997||B.A., Psychology, University of Maryland at Baltimore|
Journal articles written or co-written by Dr. James R. Munoz
Astrocytic modulation of sleep homeostasis and cognitive consequences of sleep loss Neuron (2009)
Astrocytes modulate neuronal activity by releasing chemical transmitters via a process termed gliotransmission. The role of this process in the control of behavior is unknown. Since one outcome of SNARE-dependent gliotransmission is the regulation of ...
CD133 identifies a human bone marrow stem/progenitor cell sub-population with a repertoire of secreted factors that protect against stroke Molecular Therapy (2009)
The reparative properties of bone marrow stromal cells (BMSCs) have been attributed in part to the paracrine action of secreted factors. We isolated typical human BMSCs by plastic adherence and compared them with BMSC sub-populations ...
A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice Blood (2006)
Controversies have arisen as to whether adult stem cells or progenitor cells from bone marrow can engraft into nonhematopoietic tissues in vivo. To resolve some of the controversies, we developed a highly sensitive polymerase chain ...
Role of instrumental learning in tolerance to cathinone hypophagia Behav. Neurosci. (2006)
The effects of dl-cathinone on milk intake and motor activity were investigated in bottle- and cannula-fed rats. Acute injections of cathinone produced dose-dependent increases in activity in both groups but only produced decreased intake in ...
How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow Annals of the New York Academy of Sciences (2005)
Human mesenchymal stem cells (hMSCs) from bone marrow are a source of osteoblast progenitors in vivo, and under appropriate conditions they differentiate into osteoblasts ex vivo. The cells provide a convenient cell culture model for ...
Human stem/progenitor cells from bone marrow promote neurogenesis of endogenous neural stem cells in the hippocampus of mice Proceedings of the National Academy of Sciences (2005)
Stem/progenitor cells from bone marrow and other sources have been shown to repair injured tissues by differentiating into tissue-specific phenotypes, by secreting chemokines, and, in part, by cell fusion. Here we prepared the stem/progenitor cells ...
Involvement of dopamine D2 receptor in complex maze learning and acetylcholine release in ventral hippocampus of rats Neuroscience (2001)
In the current study we focus on the involvement of dopamine D2 receptors in the ventral hippocampus in memory performance and acetylcholine release. Using the aversively motivated 14-unit T-maze (Stone maze) the injection of raclopride, ...
Aged mice exhibit greater mortality concomitant to increased brain and plasma TNF-alpha levels following intracerebroventricular injection of lipopolysaccharide Gerontology (2000)
BACKGROUND: Age-related defects in the development of peripheral inflammatory responses have been observed in rodents and humans. OBJECTIVE: We examined the effects of age on a centrally injected endotoxin-induced cytokine production and cellular activation in ...
Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats Molecular Pharmacology (1999)
ABSTRACT More and more evidence suggests that increases in dopamine (DA) in striata may participate in neurodegenerative processes during acute ischemia, hypoxia, and excitotoxicity. With a rat model of intrastriatal DA injection, we studied the ...
Intrastriatal injection of dopamine results in DNA damage and apoptosis in rats Neuroreport (1998)
Overflow of the neurotransmitter dopamine (DA) in striatum is implicated in the neurodegenerative processes in ischemia, hypoxia and local exposure to high concentrations of excitatory amino acids. However, how DA causes neurotoxicity is not understood. ...
Conference presentations, proceedings, lectures, and symposia given by Dr. James R. Munoz