Article
The enthalpy of formation of methionine revisited
Journal of Physical Organic Chemistry
(2012)
Abstract
Methionine (2‐amino‐4‐(methylthio)butanoic acid) is a sulfur‐containing essential α‐amino acid. Despite its importance, its enthalpy of formation is contentious. From the analysis of its polymorphism confirms that the previously reported calorimetric experiments were made in the temperature interval in which a phase transitions occurs. A new value for the enthalpy of formation is suggested based on these results, as well as G4 quantum chemical calculations and thermochemical estimates. From the analysis of experimental enthalpy of formation measurements, the group increment temperature adjusted enthalpy of sublimation, quantum chemical calculations, and difference quantity derived estimates, our recommended value for the gas phase enthalpy of formation of methionine is –(430 ± 10) kJ·mol−1. Copyright © 2012 John Wiley & Sons, Ltd.
Disciplines
Publication Date
January 11, 2012
DOI
10.1002/poc.2961
Citation Information
María Victoria Roux, Rafael Notario, Marta Segura, James S. Chickos, et al.. "The enthalpy of formation of methionine revisited" Journal of Physical Organic Chemistry Vol. 25 Iss. 11 (2012) p. 916 - 924 Available at: http://works.bepress.com/james-chickos/37/