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Article
HIV-Related Attention Bias and Processing Deficits in the Regulation of Emotion: An ERP Analysis
Journal of Neurophysiology and Clinical Neuroscience
  • Roger C. MacIntosh, Florida Atlantic University
  • Jaime Tartar, Nova Southeastern University
  • Susan Widmayer, Children's Diagnostic and Treatment Center
  • M Rosselli, Florida Atlantic University
Document Type
Article
Publication Date
1-1-2015
Disciplines
Peer Reviewed
1
Abstract
Deficits in emotional processing may be attributed to HIV disease or comorbid psychiatric disorders. Electrocortical markers of emotional attention, i.e., amplitude of the P2 and late positive potential (LPP), were compared between 26 HIV+ women and 25 healthy controls during an emotional regulation paradigm. HIV+ women showed early attention bias to negative stimuli indexed by greater P2 amplitude. In contrast, compared with the passive viewing of unpleasant images, HIV+ women demonstrated attenuation of the early and late LPP during positive reappraisal. This interaction remained significant after adjusting for individual differences in apathy, anxiety, and depression. Post hoc analyses implicated time since HIV diagnosis with LPP attenuation during positive reappraisal. Advancing HIV disease may disrupt neural generators associated with the cognitive reappraisal of emotions independent of psychiatric function.
DOI
10.1176/appi.neuropsych
Citation Information
Roger C. MacIntosh, Jaime Tartar, Susan Widmayer and M Rosselli. "HIV-Related Attention Bias and Processing Deficits in the Regulation of Emotion: An ERP Analysis" Journal of Neurophysiology and Clinical Neuroscience Vol. 27 Iss. 1 (2015) p. 32 - 39 ISSN: 0022-3077
Available at: http://works.bepress.com/jaime-tartar/69/