"Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels" by Jaime L. Tartar

Article

Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels

Behav Brain Res

Jaime L. Tartar, Nova Southeastern University
C.P. Ward
J.W. Cordeira
S.L. Legare
A.J. Blanchette
R.W. McCarley
R.E. Strecker

Find in your library

Document Type

Article

Publication Date

1-1-2009

Disciplines

Psychology

Abstract/Excerpt

Sleep deprivation alters mood and anxiety in man. In rats, 24 h of treadmill-induced total sleep deprivation or sleep fragmentation increased exploratory behavior in an open field test of anxiety compared to cage or exercise controls. Plasma corticosterone (CORT) levels of sleep disturbed and exercise control rats were elevated compared to cage controls, suggesting that the increased exploration observed in the sleep disturbed rats was not due to a hypothalamic-pituitary-adrenal (HPA) stress response.

DOI

10.1016/j.bbr.2008.08.035

Citation Information

Jaime L. Tartar, C.P. Ward, J.W. Cordeira, S.L. Legare, et al.. "Experimental sleep fragmentation and sleep deprivation in rats increases exploration in an open field test of anxiety while increasing plasma corticosterone levels" Behav Brain Res Vol. 197 Iss. 2 (2009) p. 450 - 453 ISSN: 0166-4328
Available at: http://works.bepress.com/jaime-tartar/37/