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Article
Cytotoxic, Antiviral Indolocarbazoles from a Blue-Green Alga Belonging to the Nostocaceae
The Journal of Antibiotics (1990)
  • G Knubel
  • L Larsen
  • R Moore
  • Ira A Levine, University of Southern Maine
  • G Patterson
Abstract

6-Cyano-5-methoxy-12-methylindolo[2,3-alpha]carbazole and 6-cyano-5-methoxyindolo[2,3-alpha]carbazole are responsible for most of the cytotoxicity and antiviral activity associated with the blue-green alga Nostoc sphaericum EX-5-1. The compounds are active against HSV II and show weak cytotoxicity against KB and LoVo human carcinoma cell lines.

Keywords
  • Antiviral,
  • blue-green alga
Publication Date
October, 1990
Publisher Statement
http://www.antibiotics.or.jp/journal/ja-top.htm
Citation Information
G Knubel, L Larsen, R Moore, Ira A Levine, et al.. "Cytotoxic, Antiviral Indolocarbazoles from a Blue-Green Alga Belonging to the Nostocaceae" The Journal of Antibiotics Vol. 43 Iss. 10 (1990)
Available at: http://works.bepress.com/ira_levine/8/