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SEROEPIDEMIOLOGY OF TOXOPLASMOSIS IN RENAL PATIENTS SEROEPIDEMIOLOGY OF TOXOPLASMOSIS IN RENAL PATIENTS
Southeast Asian Journal of Tropical Medicine and Public Health (2011)
  • Init Ithoi, University of Malaya
Abstract
Toxoplasmosis is an important parasitic disease in immunosuppressed patients. This prospective study was conducted to determine the seroprevalence, associated risk factors and the incidence of clinically confirmed toxoplasmosis among renal patients at the University of Malaya Medical Center, Kuala Lumpur, Malaysia. We interviewed 247 renal patients, each of whom answered an epidemiological questionnaire, and collected blood samples for measurement of anti-Toxoplasma IgG and IgM antibodies by ELISA. Overall seroprevalence of latent toxoplasmosis was observed in 126 (51%) renal patients. Race (Malays), marital status (married) and primary level of education, were all factors associated with a greater chance of Toxoplasma infection. A case of clinically confirned toxoplasmosis was diagnosed in a renal transplant recipient as a result of immunosuppression. Based on the findings obtained, this preliminary study shows a high prevalence of latent toxoplasmosis in renal patients. Risk factors may have significantly contributed to Toxoplasma acquisition in these patients. We recommend further studies be carried out to monitor for trends in toxoplasmosis among immunosuppressed patients.
Keywords
  • Adult,
  • Age Fact,
  • Aged,
  • 80 and over,
  • Animals,
  • Wild/parasitology,
  • Antibodies/blood,
  • Blood Transfusion/adverse effects,
  • Cats,
  • Continental Population Groups,
  • Cooking,
  • Cross-Sectional Studies,
  • Eating,
  • Educational Status,
  • Female,
  • Humans,
  • Kidney Failure,
  • Chronic/*complications,
  • Malaysia/epidemiology,
  • Male,
  • Marital Status,
  • Meat/parasitology,
  • Middle Aged,
  • Prevalence,
  • Prospective Studies,
  • Risk Factors,
  • Seroepidemiologic Studies,
  • Toxoplasma/isolation & purification,
  • Toxoplasmosis/*complications/*epidemiology/parasitology,
  • Young Adult.
Publication Date
March, 2011
Citation Information
Init Ithoi. "SEROEPIDEMIOLOGY OF TOXOPLASMOSIS IN RENAL PATIENTS SEROEPIDEMIOLOGY OF TOXOPLASMOSIS IN RENAL PATIENTS" Southeast Asian Journal of Tropical Medicine and Public Health Vol. 42 Iss. 2 (2011)
Available at: http://works.bepress.com/init_ithoi/14/