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Article
Effects of biradical deuteration on the performance of DNP: towards better performing polarizing agents
Physical Chemistry Chemical Physics
  • Frédéric A. Perras, Ames Laboratory
  • Regina R. Reinig, Iowa State University and Ames Laboratory
  • Igor I. Slowing, Iowa State University and Ames Laboratory
  • Aaron D. Sadow, Iowa State University and Ames Laboratory
  • Marek Pruski, Iowa State University and Ames Laboratory
Document Type
Article
Disciplines
Publication Version
Accepted Manuscript
Publication Date
1-1-2016
DOI
10.1039/C5CP06505D
Abstract

We study the effects of the deuteration of biradical polarizing agents on the efficiency of dynamic nuclear polarization (DNP) via the cross-effect. To this end, we synthesized a series of bTbK and TOTAPol biradicals with systematically increased deuterium substitution. The deuteration increases the radicals' relaxation time, thus contributing to a higher saturation factor and larger DNP enhancement, and reduces the pool of protons within the so-called spin diffusion barrier. Notably, we report that full or partial deuteration leads to improved DNP enhancement factors in standard samples, but also slows down the build-up of hyperpolarization. Improvements in DNP enhancements factors of up to 70% and time savings of up to 38% are obtained upon full deuteration. It is foreseen that this approach may be applied to other DNP polarizing agents thus enabling further sensitivity improvements.

Comments

This article is published as Perras, Frédéric A., Regina R. Reinig, Igor I. Slowing, Aaron D. Sadow, and Marek Pruski. "Effects of biradical deuteration on the performance of DNP: towards better performing polarizing agents." Physical Chemistry Chemical Physics 18, no. 1 (2016): 65-69. DOI: 10.1039/C5CP06505D. Posted with permission.

Copyright Owner
The Owner Societies
Language
en
File Format
application/pdf
Citation Information
Frédéric A. Perras, Regina R. Reinig, Igor I. Slowing, Aaron D. Sadow, et al.. "Effects of biradical deuteration on the performance of DNP: towards better performing polarizing agents" Physical Chemistry Chemical Physics Vol. 18 Iss. 1 (2016) p. 65 - 69
Available at: http://works.bepress.com/igor_slowing/63/