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Trends in Outcome and Hospitalization Charges of Adult Patients Admitted with Botulism in the United States.
  • Nizar Souayah, MD
  • Lubna S Mehyar
  • Hafiz M R Khan
  • Hussam A. Yacoub, MD, Lehigh Valley Health Network
  • Zaid A Al-Qudah, MD
  • Abu Nasar
  • Zubeda Begum Sheikh
  • Leila Maybodi
  • Adnan I Qureshi
Publication/Presentation Date

BACKGROUND: To assess the impact of new therapeutic strategies on outcomes and hospitalization charges among adult patients with botulism in the United States.

METHODS: We determined in-hospital outcomes and charges for patients with botulism hospitalized in 1993-1994 and compared them with those observed among patients hospitalized in 2006-2007. Mortality, length of stay, and hospitalization charges were calculated. Age, sex, race, ethnicity, and discharge status were also reported.

RESULTS: There were 66 and 132 admissions of adult patients with botulism in 1993-1994 and 2006-2007, respectively. Men predominance was observed in 2006-2007 compared to women predominance during the 1993-1994 time period. There was no significant difference in the average length of stay and in-hospital mortality rate between the two groups studied. However, in the 2006-2007 group, there was a significant increase in the mean hospitalization charges (USD 126,092 ± 120,535 vs. USD 83,623 ± 82,084; p = 0.0107) and in the proportion of patients requiring mechanical ventilation when compared to 1993-1994 (34 vs. 13.6%; p < 0.0001).

CONCLUSION: Botulism continues to be an infrequent cause of hospitalization, with a significant increase in the average hospitalization charges in 2006-2007 when compared to 1993-1994, despite a nonsignificant change in the mortality rate and average length of hospitalization.

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Citation Information

Souayah, N., Mehyar, L. S., Khan, H. R., Yacoub, H. A., Abed Al-Kariem A Al-Qudah, Z., Nasar, A., & ... Qureshi, A. I. (2012). Trends in outcome and hospitalization charges of adult patients admitted with botulism in the United States. Neuroepidemiology, 38(4), 233-236. doi:10.1159/000336354