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Pathogenesis, Clinical Course and Neuro-Radiological Signs of Proprionibacterium Acnes Cerebritis: Case Report and Literature Review.
Hosp Pract (1995)
  • Aleksandra Yakhkind, USF MCOM- LVHN Campus
  • Hussam A. Yacoub, MD, Lehigh Valley Health Network
  • Jacqueline Grove, Lehigh Valley Health Network
  • Jay D Varrato, DO, Lehigh Valley Health Network
  • John Castaldo, MD, Lehigh Valley Health Network
Publication/Presentation Date

The clinical and neuroimaging characteristics of brain infections related to Propionibacterium acnes are not well-characterized, making early diagnosis and treatment a challenge. More recently, life-threatening central nervous system infections with P. acnes are being reported with increasing frequency as complications of neurointerventional procedures. We present a rare case of P. acnes cerebritis that occurred as a sequela of bare platinum aneurysm coiling and a contaminant of percutaneous angiographic intervention. We include an extensive review of the literature describing the pathogenesis of P. acnes and neuro-radiological signs of brain infections related to this pathogen.

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Citation Information

Yakhkind, A., Yacoub, H. A., Grove, J., Varrato, J. D., & Castaldo, J. E. (2015). Pathogenesis, clinical course and neuro-radiological signs of Proprionibacterium acnes cerebritis: Case report and literature review. Hospital Practice (1995), 43(2), 128-136. doi:10.1080/21548331.2015.1017438