Article
Intramolecular Azide-Olefin Cycloadditions. A Novel Synthesis of 2,5-Dihydrooxazoles
Chemistry & Physics Faculty Publications
Document Type
Article
Publication Date
1-1-1988
Abstract
A facile synthetic route from aldehydes to allyl α-azidoalkyl ether 2 is described. Thermolysis of 2 proceeds by intramolecular azide-olefin cycloaddition via triazolines and provides a novel synthesis of 2,5-dihydrooxazoles 6. The use of silica gel in the chemoselective conversion of the intermediate triazolines to bicyclic aziridines 7 is described. © 1988, American Chemical Society. All rights reserved.
Citation Information
Alfred Hassner, Ananda S. Amarasekara and Donald Andisik. "Intramolecular Azide-Olefin Cycloadditions. A Novel Synthesis of 2,5-Dihydrooxazoles" (1988) Available at: http://works.bepress.com/httpswwwpvamuedubcasdepartmentschemistryfaculty-and-staffasamarasekara/45/