SelectedWorks - Howard Smithline MD

Contact

Selected Works of Howard Smithline MD

Department of Emergency Medicine

Works
About

×

About Howard Smithline MD

Present	Physician, Baystate Health ‐ Department of Emergency Medicine
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution
Present	Associate Professor, Tufts University School of Medicine ‐ Emergency Medicine
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Cancel

Medicine and Health Sciences

Respiratory distress, Measurement of dyspnea, and Energy metabolism

1991 Outstanding Graduating Resident Award, Henry Ford Hospital
1993 Best Resident/Fellow Oral Research Presentation, Society of Academic Emergency Medicine
1999 Best Poster Presentation, New England Regional SAEM Annual Meeting, Worcester
1998 Research Mentor Award, Emergency Medicine Department, Baystate Medical Center
1999 Research Mentor Award, Emergency Medicine Department, Baystate Medical Center
2003 Research Mentor Award, Emergency Medicine Department, Baystate Medical Center
2000-present Annual Academic Excellence Award, Baystate Medical Center

Emergency medicine residency weekly lecture series on: Pulmonary Embolism, Heart Failure, Research Methodology, Acid-Base Disorders, Asthma/COPD
Emergency medicine 4th year medical student elective monthly lecture series on the Care of Critically Ill Patients and the Care of Patients with Respiratory Distress

Baystate Health find a Provider link

Baystate Emergency Medicine
Baystate Medical Center
759 Chestnut Street
Springfield, MA  01199
Driving Directions
Phone:
(413) 794-0000
Fax:
(413) 794-8070

Effectiveness of a bivalent mRNA vaccine dose against symptomatic SARS-CoV-2 infection among U.S. Healthcare personnel, September 2022-May 2023 (Howard Smithline) All Scholarly Works (2023)

Background: Bivalent mRNA vaccines were recommended since September 2022. However, coverage with a recent vaccine dose has been limited, and there are few robust estimates of bivalent VE against symptomatic SARS-CoV-2 infection (COVID-19). We estimated ...

Effectiveness of a Messenger RNA Vaccine Booster Dose Against Coronavirus Disease 2019 Among US Healthcare Personnel, October 2021-July 2022 (Howard Smithline) All Scholarly Works (2023)

Background: Protection against symptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019 [COVID-19]) can limit transmission and the risk of post-COVID conditions, and is particularly important among healthcare personnel. However, lower vaccine ...

Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel (Howard Smithline) All Scholarly Works (2021)

Background: The prioritization of U.S. health care personnel for early receipt of messenger RNA (mRNA) vaccines against severe acute respiratory disease coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19), allowed for the ...

Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2019)

BACKGROUND: The purpose of this pilot study was to determine if a definitive clinical trial of thiamine supplementation was warranted in patients with acute heart failure. We hypothesized that thiamine, when added to standard of ...

Supplemental thiamine for the treatment of acute heart failure syndrome: a randomized controlled trial (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2019)

BACKGROUND: The purpose of this pilot study was to determine if a definitive clinical trial of thiamine supplementation was warranted in patients with acute heart failure. We hypothesized that thiamine, when added to standard of ...

An example of medical device-based projection of clinical trial enrollment: Use of electrocardiographic data to identify candidates for a trial in acute coronary syndromes (Howard Smithline) All Scholarly Works (2018)

Background: To identify potential participants for clinical trials, electronic health records (EHRs) are searched at potential sites. As an alternative, we investigated using medical devices used for real-time diagnostic decisions for trial enrollment. Methods: To ...

Prevalence of Inconsistencies in the Recorded Outcomes of Clinical Evaluations (Blake Spirko, Howard Smithline and Jane Garb) All Scholarly Works (2017)

OBJECTIVES: The aims of the study were to determine the prevalence of variations in the recorded outcomes of clinical evaluations by 2 different physicians during a single patient visit and to comment on observations of ...

Corticosteroid therapy in refractory shock following cardiac arrest: a randomized, double-blind, placebo-controlled, trial (Howard Smithline) All Scholarly Works (2016)

BACKGROUND: The purpose of this study was to determine whether the provision of corticosteroids improves time to shock reversal and outcomes in patients with post-cardiac arrest shock. METHODS: We conducted a randomized, double-blind trial of ...

Randomized, Double-Blind, Placebo-Controlled Trial of Thiamine as a Metabolic Resuscitator in Septic Shock: A Pilot Study (Mark Tidswell and Howard Smithline) All Scholarly Works (2016)

OBJECTIVE: To determine if intravenous thiamine would reduce lactate in patients with septic shock. DESIGN: Randomized, double-blind, placebo-controlled trial. SETTING: Two US hospitals. PATIENTS: Adult patients with septic shock and elevated (> 3 mmol/L) lactate ...

Randomized Controlled Trial of Electronic Care Plan Alerts and Resource Utilization by High Frequency Emergency Department Users with Opioid Use Disorder (Niels Rathlev, Ashley Deutsch, Howard Smithline, et al.) All Scholarly Works (2016)

INTRODUCTION: There is a paucity of literature supporting the use of electronic alerts for patients with high frequency emergency department (ED) use. We sought to measure changes in opioid prescribing and administration practices, total charges ...

Emergency medicine residents' knowledge of mechanical ventilation (Howard Smithline and Lucienne Lutfy-Clayton) All Scholarly Works (2015)

BACKGROUND: Although Emergency physicians frequently intubate patients, management of mechanical ventilation has not been emphasized in emergency medicine (EM) residency curricula. OBJECTIVES: The objective of this study was to quantify EM residents' education, experience, and ...

Independent evaluation of a simple clinical prediction rule to identify right ventricular dysfunction in patients with shortness of breath (Howard Smithline) All Scholarly Works (2015)

BACKGROUND: Many patients have unexplained persistent dyspnea after negative computed tomographic pulmonary angiography (CTPA). We hypothesized that many of these patients have isolated right ventricular (RV) dysfunction from treatable causes. We previously derived a clinical ...

A randomized trial of benralizumab, an antiinterleukin 5 receptor α monoclonal antibody, after acute asthma (Howard Smithline) All Scholarly Works (2015)

BACKGROUND: Patients with frequent asthma exacerbations resulting in emergency department (ED) visits are at increased risk for future exacerbations. We examined the ability of 1 dose of benralizumab, an investigational antiinterleukin 5 receptor α monoclonal ...

Body Mass Index and Risk of Hospitalization among Adults Presenting with Asthma Exacerbation to the Emergency Department (Howard Smithline) All Scholarly Works (2014)

RATIONALE: Studies have linked obesity to incident asthma and worse chronic severity/control. However, the relationship between obesity and acute asthma morbidity remains unclear. OBJECTIVES: To determine whether obese adults presenting to the emergency department (ED) ...

Mismatch in ED and Discharge Diagnoses of CHF (Howard Smithline, Sunjin Oh and Nicholas Cormier) All Scholarly Works (2014)

Evaluation of dyspnea severity assessment methods (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2013)

Supplemental thiamine for the treatment of acute heart failure (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2013)

Electrolyte profile of pediatric patients with hypertrophic pyloric stenosis (Geoffrey A Capraro, Blake Spirko, Jane Garb, et al.) All Scholarly Works (2013)

OBJECTIVES: Recent investigations have demonstrated that the classic hypochloremic, hypokalemic, metabolic alkalosis of hypertrophic pyloric stenosis (HPS) is not a common finding.Some have suggested a trend over time, but none has investigated factors contributing to ...

Evaluation of dyspnea severity assessment methods (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2013)

Supplemental thiamine for the treatment of acute heart failure (Howard Smithline, Fidela Blank, Richard Barus, et al.) All Scholarly Works (2013)

Evaluation of pulmonary embolism in the emergency department and consistency with a national quality measure: quantifying the opportunity for improvement (Howard Smithline) All Scholarly Works (2012)

BACKGROUND: The National Quality Forum (NQF) has endorsed a performance measure designed to increase imaging efficiency for the evaluation of pulmonary embolism (PE) in the emergency department (ED). To our knowledge, no published data have ...

Correlation between change in dyspnea severity and clinical outcome in patients with acute heart failure (Howard Smithline, Richard Barus, Fidela Blank, et al.) All Scholarly Works (2012)

D-Dimer threshold increase with pretest probability unlikely for pulmonary embolism to decrease unnecessary computerized tomographic pulmonary angiography (Howard Smithline) All Scholarly Works (2012)

BACKGROUND: Increasing the threshold to define a positive D-dimer could reduce unnecessary computed tomographic pulmonary angiography (CTPA) for a suspected pulmonary embolism (PE) but might increase rates of a missed PE and missed pneumonia, the ...

Use of magnetic resonance imaging to measure endothelial function (Howard Smithline) All Scholarly Works (2012)

Using acoustic analysis of coughs to identify respiratory infections in the emergency department (Howard Smithline, Ryan Coute and Richard Barus) All Scholarly Works (2012)