In recent years, it has been used time-series analysis to characterize complex biochemical oscillations. The aim of this work is to show that fractal analysis has the ability to provide further information on biochemical mechanisms leading to complex biochemical oscillations. Analysis of simulated and experimental time-series data for two systems, intracellular calcium and circadian oscillations, is made in order to illustrate the relation between fractal parameters and biochemical mechanisms leading to complex oscillations. For completeness, standard non-linear analysis, such as delayed phase-plane reconstruction and lyapunov exponents, is also performed.
- Fractal analysis,
- biochemical oscillations,
- time series
Available at: http://works.bepress.com/hector_puebla/19/