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Article
Evaluation of Stature Development During Childhood and Adolescence in Individuals with Familial Hypophosphatemic Rickets
The Scientific World Journal
  • Mauro M. S. Borghi, Faculty of Medical Sciences, Brazil
  • Verônica Coates, Faculty of Medical Sciences, Brazil
  • Hatim A. Omar, University of Kentucky
Abstract

This review was conducted to study the diagnosis, treatment, and growth progression in infants and adolescents with familial hypophosphatemic rickets. The bibliographic search was carried out utilizing the electronic databases MEDLINE, OVID, and LILACS and by direct research within the last 15 years using the keywords rickets, familial hypophosphatemia, vitamin D deficiency, stature growth, childhood, and adolescence. Article selection was done by comparing the evaluation of the growth in patients with familial hypophosphatemic rickets, including the variables that might affect them, for possible future therapeutic proposals. It is concluded that the most significant fact in the treatment of familial hypophosphatemic rickets in infancy was the magnitude of the final stature. The use of growth hormone can be helpful in these patients. However, research reporting treatments with the use of the growth hormone for rickets are controversial. The majority of the authors agree that treatment using vitamin D and phosphate enables some statural growth in cases of early diagnosis, reflecting a better prognosis.

Document Type
Article
Publication Date
10-17-2005
Disciplines
Notes/Citation Information

Published in The Scientific World Journal, v. 5, p. 868-873.

Copyright © 2005 Mauro M.S. Borghi et al.

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided that the original work is properly cited.

Digital Object Identifier (DOI)
http://dx.doi.org/10.1100/tsw.2005.102
Citation Information
Mauro M. S. Borghi, Verônica Coates and Hatim A. Omar. "Evaluation of Stature Development During Childhood and Adolescence in Individuals with Familial Hypophosphatemic Rickets" The Scientific World Journal Vol. 5 (2005) p. 868 - 873
Available at: http://works.bepress.com/hatim_omar/68/