The Origins Spectral Interpretation, Resource Identification, and Security-Regolith Explorer (OSIRIS-REx) spacecraft launched flawlessly on September 8, 2016, as NASA's third New Frontiers mission. The primary requirement of the OSIRIS-REx mission is to collect and return a pristine sample from the surface of a near-Earth asteroid. OSIRIS-REx will arrive at B-type asteroid (101955) Bennu [1] in August 2018. This asteroid was targeted owing to its spectral similarity to carbonaceous chondrites, appropriate size, and favorable orbit. After detailed geological and spectral mapping, OSIRIS-REx will collect up to 2 kg of surface regolith samples from a carefully-selected site in mid-2020. The surface regolith from Bennu will be pristine samples with a record of the entire history of Bennu from the interstellar medium to the recent dynamical evolution and surface geological processes [2]. The sample return capsule will deliver these samples to the Earth in September 2023.