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Article
Magnetic nanoparticle drug delivery systems for targeting tumor
Applied Nanoscience
  • Vicky V. Mody
  • Arthur Cox
  • Samit Shah
  • Ajay Singh
  • Wesley Bevins
  • Harish S. Parihar, Philadelphia College of Osteopathic Medicine
Document Type
Article
Publication Date
1-1-2013
Abstract

Tumor hypoxia, or low oxygen concentration, is a result of disordered vasculature that lead to distinctive hypoxic microenvironments not found in normal tissues. Many traditional anti-cancer agents are not able to penetrate into these hypoxic zones, whereas, conventional cancer therapies that work by blocking cell division are not effective to treat tumors within hypoxic zones. Under these circumstances the use of magnetic nanoparticles as a drug delivering agent system under the influence of external magnetic field has received much attention, based on their simplicity, ease of preparation, and ability to tailor their properties for specific biological applications. Hence in this review article we have reviewed current magnetic drug delivery systems, along with their application and clinical status in the field of magnetic drug delivery.

Comments

This article was published in Applied Nanoscience, Volume 4, Pages 385-392.

The published version is available at http://dx.doi.org/10.1007/s13204-013-0216-y.

© 2013 The Authors. This article if published with open access at Springerlink.com

Citation Information
Vicky V. Mody, Arthur Cox, Samit Shah, Ajay Singh, et al.. "Magnetic nanoparticle drug delivery systems for targeting tumor" Applied Nanoscience Vol. 4 (2013) p. 385 - 392
Available at: http://works.bepress.com/harish_parihar/10/