Objectives:

To study the outcome and safety of semirigid ureteroscopy (URS) using pneumatic lithotripsy for treatment of ureteral stones of surface area > 30 mm(2) and to assess the impact of size and location on stone-free (SF) rate. Patients and

Methods:

In this study, 265 Patients with > 30 mm(2) isolated ureteral stones treated by semirigid URS were included. URS was performed using an 8F, 7F, or 6.4F semirigid ureteroscopes with pneumatic lithotripsy (Swiss Lithoclast (TM)). Stones were fragmented to similar to 2-3 mm particles, and removed. The outcome parameters assessed at 3-month follow-up were SF rate and efficiency quotient (EQ), impact of stone size and site on SF/EQ was also analyzed. The Patient demographics, stone, procedure, and Patient-related parameters and complications were noted.

Results:

At 3-month follow-up overall SF was 74% and EQ 59.2%. SF for 30-100 mm(2) and > 100 mm(2) was 79.2% and 68.5%, respectively (p < 0.003). The SF/EQ for upper, middle, and lower ureteral stones were 59/40.7, 53/37.5, and 92/84.5, respectively (p < 0.001). There was no major complication, the minor complication rate was 12.5%. Conclusions: Semirigid URS using pneumatic lithotripsy for treatment of stones > 30 mm(2) is a safe and highly efficacious procedure particularly in the distal ureter. There is a significant difference in the SF and EQ between upper/middle ureteral stone and lower ureteral stone. Stone size has a direct relation with the SF and EQ. Upper ureteral stones have a longer time to SF compared to middle and lower ureteral stones (p < 0.001).