Article
Hydrolyzed Octadecyltrichlorosilane Functionalized with Amino Acid as Heterogeneous Enantioselective Catalaysts
Reaction Kinetics and Catalysis Letters
(2009)
Abstract
Heterogeneous asymmetric catalysts using amino acid as chiral promoter were synthesized by attachment of amino acids such as L-glutamic acid and L-phenylalanine onto the hydrophilic part of hydrolyzed octadecyltrichlorosilane (OTS). The catalysts exhibit 12-18% enantiomeric excess (ee) for the asymmetric hydration of epoxycyclohexene to yield (1R,2R)-trans-1,2-cyclohexanediol and (1S,2S)-trans-1,2-cyclohexanediol.
Keywords
- heterogeneous asymmetric catalysts,
- amino acid as chiral promoter,
- asymmetric hydration of epoxycyclohexene
Disciplines
Publication Date
2009
Citation Information
Hadi Nur, Lim Kheng Wei and Salasiah Endud. "Hydrolyzed Octadecyltrichlorosilane Functionalized with Amino Acid as Heterogeneous Enantioselective Catalaysts" Reaction Kinetics and Catalysis Letters Vol. in press (2009) Available at: http://works.bepress.com/hadi_nur/48/