Article
Evaluation of in vitro corrosion behavior and biocompatibility of polyxylitol-(1,12-dodecanedioate)-HA coated porous iron for bone scaffolds applications
Biotechnology Journal
(2024)
Abstract
The present study evaluates the corrosion behavior of poly[xylitol-(1,12-dodecanedioate)](PXDD)-HA coated porous iron (PXDD140/HA-Fe) and its cell-material interaction aimed for temporary bone scaffold applications. The physicochemical analyses show that the addition of 20 wt.% HA into the PXDD polymers leads to a higher crystallinity and lower surface roughness. The corrosion assessments of the PXDD140/HA-Fe evaluated by electrochemical methods and surface chemistry analysis indicate that HA decelerates Fe corrosion due to a lower hydrolysis rate following lower PXDD content and being more crystalline. The cell viability and cell death mode evaluations of the PXDD140/HA-Fe exhibit favorable biocompatibility as compared to bare Fe and PXDD-Fe scaffolds owing to HA's bioactive properties. Thus, the PXDD140/HA-Fe scaffolds possess the potential to be used as a biodegradable bone implant.
Disciplines
Publication Date
March, 2024
DOI
10.1002/biot.202300464
Citation Information
Abdul Hakim Md Yusop, Wan Fahmin Faiz Wan Ali, Farah Hidayah Jamaludin, Fatihhi Szali Januddi, et al.. "Evaluation of in vitro corrosion behavior and biocompatibility of polyxylitol-(1,12-dodecanedioate)-HA coated porous iron for bone scaffolds applications" Biotechnology Journal Vol. 19 Iss. 3 (2024) p. e2300464 ISSN: 1860-7314 Available at: http://works.bepress.com/hadi_nur/259/