Mesostructured Technische Universiteit Delft-Crystalline (TUD-C), a hierarchical zeolitic material with MFI framework was used for the first time as catalyst support for the olefins epoxidation. While TUD-C and molybdena doped titania showed considerably low catalytic activities, the molybdena doped titania supported on TUD-C exhibited significantly improved catalytic activities with 100% selectivity. Both properties and catalytic performance of the materials were greatly affected by the molar ratio of Si/Al in the TUD-C. It has been demonstrated that MoeTiO2 supported on TUD-C with Si/Al ¼ 10 was an excellent oxidative catalyst for epoxidation of various types of olefins. Kinetics study revealed that the catalytic reactions followed the first order model.