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Article
Management of recurrent hepatitis C after liver transplantation: a concise review
Gastroenterology Publications and Presentations
  • Gyongyi Szabo, University of Massachusetts Medical School
  • Eliezer Katz, University of Massachusetts Medical School
  • Herbert L. Bonkovsky
UMMS Affiliation
Department of Medicine, Division of Gastroenterology
Publication Date
9-28-2000
Document Type
Article
Subjects
Antiviral Agents; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Interferon-alpha; Liver Transplantation; Prognosis; RNA, Viral; Recurrence; Ribavirin
Disciplines
Abstract
Recurrent hepatitis C infection and subsequent graft failure are increasingly recognized problems after orthotopic liver transplantation. Although many prospective therapeutic, controlled trials in primary hepatitis C disease have been reported, large-scale studies are yet to be performed in patients with posttransplant recurrent hepatitis C after liver transplantation. In this review, we summarize the current literature on the therapeutic approaches for recurrent hepatitis C and discuss the results of published studies on therapy with ribavirin or interferon (IFN) alone and on combination therapy with IFN plus ribavirin. Further, we discuss results of prophylactic approaches to the problem of recurrent hepatitis C after transplant. Finally, we discuss additional aspects of anti-hepatitis C virus therapy after liver transplantation.
DOI of Published Version
10.1111/j.1572-0241.2000.02296.x
Source
Am J Gastroenterol. 2000 Sep;95(9):2164-70. Link to article on publisher's site
Related Resources
Link to Article in PubMed
PubMed ID
11007212
Citation Information
Gyongyi Szabo, Eliezer Katz and Herbert L. Bonkovsky. "Management of recurrent hepatitis C after liver transplantation: a concise review" Vol. 95 Iss. 9 (2000) ISSN: 0002-9270 (Linking)
Available at: http://works.bepress.com/gyongyi_szabo/64/