Article
Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes
Chemical Communications
(2015)
Abstract
Diastereopure substituted diaziridines from simple ketones, aldehydes and amines are here reported. These important chemical scaffolds are obtained in the presence of a weak inorganic base and hydroxylamine O-sulfonic acid (HOSA). This method introduces three stereocenters in one step to provide a wide variety of substituted diaziridines with high yields and diastereoselectivities.
Disciplines
Publication Date
2015
DOI
10.1039/C5CC04813C
Citation Information
Alexander W. Beebe, Emma F. Dohmeier and Gustavo Moura-Letts. "Diastereoselective synthesis of substituted diaziridines from simple ketones and aldehydes" Chemical Communications Vol. 51 (2015) p. 13511 - 13514 Available at: http://works.bepress.com/gustavo-moura-letts/8/