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Fast Disinfecting Antimicrobial Surfaces
Langmuir (2009)
  • Ahmad E. Madkour, University of Massachusetts - Amherst
  • Jeffery M. Dabkowski, University of Massachusetts - Amherst
  • Klaus Nüsslein, University of Massachusetts - Amherst
  • Gregory N. Tew, University of Massachusetts - Amherst

Silicon wafers and glass surfaces were functionalized with facially amphiphilic antimicrobial copolymers using the "grafting from" technique. Surface-initiated atom transfer radical polymerization (ATRP) was used to grow poly(butylmethacrylate)-co-poly(Boc-aminoethyl methacrylate) from the surfaces. Upon Boc-deprotection, these surfaces became highly antimicrobial and killed S. aureus and E. coli 100% in less than 5 min. The molecular weight and grafting density of the polymer were controlled by varying the polymerization time and initiator surface density. Antimicrobial studies showed that the killing efficiency of these surfaces was independent of polymer layer thickness or grafting density within the range of surfaces studied.

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Ahmad E. Madkour, Jeffery M. Dabkowski, Klaus Nüsslein and Gregory N. Tew. "Fast Disinfecting Antimicrobial Surfaces" Langmuir Vol. 25 Iss. 2 (2009)
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