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Addition/Elimination Reactions of Ethylsulfonyl Pyridines: Stereoselective Synthesis of Vinylpyridine Allylic Alcohols
Tetrahedron Letters (2013)
  • Gregory W. O'Neil
  • Nathan D. Drake
  • Jennifer M. Storvick
Abstract
2-(Phenylsulfonyl)ethyl pyridines can be coupled with aldehydes leading directly to sulfone-eliminated vinylpyridine allylic alcohols. These products are obtained in good yield and with high levels of stereocontrol.
Keywords
  • Pyridine,
  • Sulfone,
  • Addition/elimination,
  • Stereoselective,
  • Heterocycle
Disciplines
Publication Date
February 13, 2013
DOI
10.1016/j.tetlet.2012.12.049
Publisher Statement
Copyright © 2012 Elsevier Ltd. All rights reserved.
Citation Information
Gregory W. O'Neil, Nathan D. Drake and Jennifer M. Storvick. "Addition/Elimination Reactions of Ethylsulfonyl Pyridines: Stereoselective Synthesis of Vinylpyridine Allylic Alcohols" Tetrahedron Letters Vol. 54 Iss. 7 (2013) p. 715 - 7171
Available at: http://works.bepress.com/gregory_oneil/9/