"Toward the Total Synthesis of Spirastrellolide A. Part 3: Intelligence Gathering and Preparation of a Ring-expanded Analogue" by Gregory W. O'Neil

Article

Toward the Total Synthesis of Spirastrellolide A. Part 3: Intelligence Gathering and Preparation of a Ring-expanded Analogue

Chemical Communication (2007)

Gregory W. O'Neil
Alois Fürstner
Bernhard Fasching
Michaël D. B. Fenster
Cèdrickx Godbout

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Abstract

Different methods for the formation of the C.25–C.26 bond of spirastrellolide A (1) are evaluated that might qualify for the end game of the projected total synthesis, with emphasis on metathetic ways to forge the macrocyclic frame.

Keywords

spriastrellolide A,
Metathetic way,
Macrocyclic frame

Disciplines

Organic Chemistry

Publication Date

2007

DOI

10.1039/B707835H

Publisher Statement

Citation Information

Gregory W. O'Neil, Alois Fürstner, Bernhard Fasching, Michaël D. B. Fenster, et al.. "Toward the Total Synthesis of Spirastrellolide A. Part 3: Intelligence Gathering and Preparation of a Ring-expanded Analogue" Chemical Communication Vol. 2007 Iss. 29 (2007) p. 3045 - 3047
Available at: http://works.bepress.com/gregory_oneil/20/