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Selected Works of Gregory W. O'Neil
Article
Total Synthesis of Spirastrellolide F Methyl Ester—Part 2: Macrocyclization and Completion of the Synthesis
Angewandte Chemie (2009)
  • Gregory W. O'Neil
  • Stefan Benson
  • Marie-Pierre Collin
  • Julien Ceccon
  • Bernhard Fasching
  • Michaël D.B. Fenster
  • Cèdrickx Godbout
  • Karin Radkowski
  • Richard Goddard
  • Alois Fürstner
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Abstract
Wonder Lake: The compact and highly convergent total synthesis of the methyl ester of the marine macrolide spirastrellolide F was completed. The northern and southern "hemispheres" in only two stages were without intermediate protecting group manipulations combined (Suzuki coupling, Yamaguchi lactonization).
Keywords
  • Marine macrolide spirastrellolide F
Disciplines
Publication Date
December, 2009
DOI
10.1002/ange.200906122
Publisher Statement
Copyright © 1999 - 2016 John Wiley & Sons, Inc. All Rights Reserved
Citation Information
Gregory W. O'Neil, Stefan Benson, Marie-Pierre Collin, Julien Ceccon, et al.. "Total Synthesis of Spirastrellolide F Methyl Ester—Part 2: Macrocyclization and Completion of the Synthesis" Angewandte Chemie Vol. 121 Iss. 52 (2009) p. 10130 - 10134
Available at: http://works.bepress.com/gregory_oneil/18/