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Article
Synthesis and Activity of the Archazolid Western Hemisphere
Organic & Biomolecular Chemistry (2011)
  • Gregory W. O'Neil
  • Ann B. Tran, Western Washington University
  • Geoffrey C. Melly, Western Washington University
  • Ryan Doucette, Western Washington University
  • Brook Ashcraft, Western Washington University
  • Leanne J. Sebren, Western Washington University
  • Nathan Havko, Western Washington University
  • Jeffery C. Young, Western Washington University
Abstract
A convergent and scalable synthesis of the archazolid western hemisphere has been completed. The V-ATPase inhibitory activity of this compound along with a previously prepared eastern domain was then tested using a convenient Arabidopsis-based V-ATPase assay.
Keywords
  • Archazoilid western hemisphere,
  • Scalable synthesis
Disciplines
Publication Date
2011
DOI
10.1039/C1OB06446K
Publisher Statement
© Royal Society of Chemistry 2016
Citation Information
Gregory W. O'Neil, Ann B. Tran, Geoffrey C. Melly, Ryan Doucette, et al.. "Synthesis and Activity of the Archazolid Western Hemisphere" Organic & Biomolecular Chemistry Vol. 9 (2011) p. 7671 - 7674
Available at: http://works.bepress.com/gregory_oneil/11/