We present three new semi-Lagrangian methods based on radial basis function (RBF) interpolation for numerically simulating transport on a sphere. The methods are mesh-free and are formulated entirely in Cartesian coordinates, thus avoiding any irregular clustering of nodes at artificial boundaries on the sphere and naturally bypassing any apparent artificial singularities associated with surface-based coordinate systems. For problems involving tracer transport in a given velocity field, the semi-Lagrangian framework allows these new methods to avoid the use of any stabilization terms (such as hyperviscosity) during time-integration, thus reducing the number of parameters that have to be tuned. The three new methods are based on interpolation using 1) global RBFs, 2) local RBF stencils, and 3) RBF partition of unity. For the latter two of these methods, we find that it is crucial to include some low degree spherical harmonics in the interpolants. Standard test cases consisting of solid body rotation and deformational flow are used to compare and contrast the methods in terms of their accuracy, efficiency, conservation properties, and dissipation/dispersion errors. For global RBFs, spectral spatial convergence is observed for smooth solutions on quasi-uniform nodes, while high-order accuracy is observed for the local RBF stencil and partition of unity approaches.