SelectedWorks - Grace Makari-Judson MD

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Selected Works of Grace Makari-Judson MD

Co-Director, The Rays of Hope Center for Breast Cancer Research

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About Grace Makari-Judson MD

Present	Assistant Professor of Medicine, Tufts University School of Medicine
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Present	Chair, Baystate Health Breast Network, Baystate Health
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Present	Co-Director, The Rays of Hope Center for Breast Cancer Research, Baystate Health
Institution Organization Position Type Position Title Time Period to Options Current Position Affiliate my profile with this Institution

Medicine and Health Sciences

Baystate Education and Research

Baystate Regional Cancer Program - Hematology and Oncology
D'Amour Center for Cancer Care
3350 Main Street
Springfield, MA 01107

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Alternating 17β-Estradiol and Aromatase Inhibitor Therapies Is Efficacious in Postmenopausal Women with Advanced Endocrine-Resistant ER+ Breast Cancer (Grace Makari-Judson) All Scholarly Works (2023)

Purpose: Strategies to implement estrogen therapy for advanced estrogen receptor-positive (ER+) breast cancer are underdeveloped. Preclinical data suggest that cycling treatment with 17β-estradiol followed by estrogen deprivation can control tumor growth long-term. Patients and methods: ...

Alternating 17beta-estradiol and aromatase inhibitor therapies is efficacious in post-menopausal women with advanced endocrine-resistant ER+ breast cancer (Grace Makari-Judson) All Scholarly Works (2023)

Purpose: Strategies to implement estrogen therapy for advanced estrogen receptor (ER)-positive breast cancer are under-developed. Preclinical data suggest that cycling treatment with 17b-estradiol followed by estrogen deprivation can control tumor growth long-term. Experimental design: Post-menopausal ...

Outcomes of a Multidisciplinary Team in the Management of Patients with Early-Stage Breast Cancer Undergoing Neoadjuvant Chemotherapy at a Community Cancer Center (Prarthna Bhardwaj, Holly Mason, Seth Kaufman, et al.) All Scholarly Works (2023)

Background: The utilization of neoadjuvant chemotherapy (NAC) remains highly variable in clinical practice. The implementation of NAC requires coordination of handoffs between a multidisciplinary team (MDT). This study aims to assess the outcomes of an ...

Experiences of individuals with a variant of uncertain significance on genetic testing for hereditary cancer risks: a mixed method systematic review (Grace Makari-Judson) All Scholarly Works (2022)

The expansion of Multi-Gene Panel Testing (MGPT) has led to increased detection of variants of uncertain significance (VUS) among individuals with personal or family history of cancer. However, having a VUS result can impact on ...

Interindividual variation contributes to differential PCB 126 induced gene expression in primary breast epithelial cells and tissues (Stephanie M Morin, Giovanna Crisi, Kelly Gregory, et al.) All Scholarly Works (2022)

PCB 126 is a pervasive, dioxin-like chemical pollutant which can activate the aryl hydrocarbon receptor (AhR). Despite being banned from the market, PCB 126 can be detected in breast milk to this day. The extent ...

Mode of Detection of Second Events in Routine Surveillance of Early Stage Breast Cancer Patients (Soe Min Tun, Sunitha Alluri, Vida Rastegar, et al.) All Scholarly Works (2022)

Introduction: NCCN and ASCO guidelines recommend breast cancer (BC) follow-up to include clinical breast examination (CBE) every 6 months and annual mammography (AM) for 5 years. Given limited data to support CBE, we evaluated the ...

Insulin resistance and weight gain in women treated for early stage breast cancer (Grace Makari-Judson, Deborah Katz, Ruth Barham, et al.) All Scholarly Works (2022)

Purpose: Both weight gain and insulin resistance have been associated with poorer prognosis in women receiving adjuvant therapy for early stage breast cancer, however, interactions between weight gain and insulin resistance have not been explored ...

Inter-Individual Variation in Response to Estrogen in Human Breast Explants (Jennifer Ser-Dolansky, Sallie Schneider, Grace Makari-Judson, et al.) All Scholarly Works (2020)

Exposure to estrogen is strongly associated with increased breast cancer risk. While all women are exposed to estrogen, only 12% are expected to develop breast cancer during their lifetime. These women may be more sensitive ...

Metrics of diabetes risk are only minimally improved by exercise training in postmenopausal breast cancer survivors (Grace Makari-Judson) All Scholarly Works (2019)

CONTEXT: Insulin resistance is a risk factor for breast cancer recurrence. How exercise training changes fasting and post-glucose insulin resistance in breast cancer survivors is unknown. OBJECTIVE: To evaluate exercise-induced changes in post-glucose ingestion insulin ...

Gene expression signature of atypical breast hyperplasia and regulation by SFRP1 (Kelly Gregory, Giovanna Crisi, Brooke Bentley, et al.) All Scholarly Works (2019)

BACKGROUND: Atypical breast hyperplasias (AH) have a 10-year risk of progression to invasive cancer estimated at 4-7%, with the overall risk of developing breast cancer increased by ~ 4-fold. AH lesions are estrogen receptor alpha ...

Nursing Poster - 2019 (Rachel K Walker, Richard Viskochil, Jeanne Gagliarucci, et al.) Research and Education Posters (2019)

Nursing Posters - 2019

Bisphenol-A in breast adipose tissue of breast cancer cases and controls (Sallie Schneider, Holly Mason, Melissa Johnson, et al.) All Scholarly Works (2018)

We evaluated whether bisphenol-A (BPA) could be quantified in breast adipose tissue samples provided by 36 breast cancer mastectomy patients and 14 reduction mammoplasty patients. Samples of breast adipose tissue were collected and BPA concentration ...

Individual-specific Variation in the Respiratory Activities of HMECs and Their Bioenergetic Response to IGF1 and TNFα (Sallie Schneider, Elizabeth Henchey, Nazeen Sultana, et al.) All Scholarly Works (2017)

Metabolic reprograming is a hallmark of cancer cells. However, the roles of pre-existing differences in normal cells metabolism toward cancer risk is not known. In order to assess pre- existing variations in normal cell metabolism, ...

Longitudinal patterns of weight gain after breast cancer diagnosis: Observations beyond the first year. (Grace Makari-Judson and Wilson Mertens) All Scholarly Works (2007)

Many, but not all patients experience weight gain 1 year after a breast cancer diagnosis; clearly defined, clinically relevant groups at risk of weight gain have yet to be described. We set out to determine ...

Gene Expression Profiles Identify Features Common to Lobular and Ductal Premalignant Breast Lesions (Amy L. Roberts, D. Joseph Jerry, Kelly J. Gauger, et al.) UMass Center for Clinical and Translational Science Research Symposium (2014)

Premalignant lesions have been identified in both the ductal and lobular units of the breast epithelium. These lesions have a 4-fold increase in risk of progression to invasive breast cancer, but 80% will remain indolent. ...

Using quality oncology practice initiative metrics for physician incentive compensation (Grace Makari-Judson, Tamara Wrenn, Wilson Mertens, et al.) All Scholarly Works (2014)

PURPOSE: To demonstrate the use of American Society of Clinical Oncology (ASCO) Quality Oncology Practice Initiative (QOPI) measures as part of a financial incentive plan for an academic health center-based hematology-oncology division. METHODS: An 11-member ...

Pregnancy offers new insights into mechanisms of breast cancer risk and resistance (D. Joseph Jerry, Grace Makari-Judson, Giovanna Crisi, et al.) All Scholarly Works (2013)

Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent ...

Use of survivorship care plans to re-engineer brest cancer follow-up (Grace Makari-Judson, Sandra Hubbard and Tamara Wrenn) All Scholarly Works (2013)

Background: Optimal strategies for quality care of breast cancer survivors include providing value in each visit and appropriately utilizing resources. The purpose of this study was to demonstrate the use of Survivorship Care Plans (SCPs) ...

Sorafenib or placebo with either gemcitabine or capecitabine in patients with HER-2-negative advanced breast cancer that progressed during or after bevacizumab (Grace Makari-Judson) All Scholarly Works (2013)

PURPOSE: We assessed adding the multikinase inhibitor sorafenib to gemcitabine or capecitabine in patients with advanced breast cancer whose disease progressed during/after bevacizumab. EXPERIMENTAL DESIGN: This double-blind, randomized, placebo-controlled phase IIb study (ClinicalTrials.gov NCT00493636) enrolled ...

Use of survivorship care plans to re-engineer breast cancer follow-up (Grace Makari-Judson, Sandra Hubbard and Tamara Wrenn) All Scholarly Works (2012)

Using QOPI metrics for physician incentive compensation (Grace Makari-Judson, Tamara Wrenn, Wilson Mertens, et al.) All Scholarly Works (2012)

Spectrum of breast disease encountered in HIV-positive patients at a community teaching hospital (Liron Pantanowitz, Sabyasachi Sen, Giovanna Crisi, et al.) All Scholarly Works (2011)

INTRODUCTION: HIV infection directly and indirectly affects breast tissue. This study describes the spectrum of HIV-related breast disease encountered at a community teaching hospital. METHODS: A 9 year retrospective review was performed of HIV-positive patients ...

Breast cancer survivors perceptions regarding relapse and related disease risk (Grace Makari-Judson, Chandravathi Loke, Deborah Katz, et al.) All Scholarly Works (2011)

Recalling breast cancer presentation and therapy: Associations between patient inaccuracies and demographic characteristics (Wilson Mertens, Chandravathi Loke, Deborah Katz, et al.) All Scholarly Works (2011)