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Article
Pregnancy offers new insights into mechanisms of breast cancer risk and resistance
All Scholarly Works
  • D. Joseph Jerry, Baystate Health
  • Grace Makari-Judson, MD, Baystate Health
  • Giovanna Crisi, MD, Baystate Health
  • Karen Dunphy, Baystate Health
Document Type
Article, Peer-reviewed
Publication Date
9-1-2013
Abstract
Pregnancy induces long-lasting changes in gene expression that are associated with a reduction in breast cancer risk. Although several mechanisms have been proposed to mediate the reduction in breast cancer risk among parous women, recent studies focus attention on progenitor cells as major targets. The results suggest new biomarkers that may improve risk prediction and provide endpoints for assessment of clinical responses to prophylactic therapies.
Citation Information
Jerry DJ, Makari-Judson G, Crisi GM, Dunphy KA. Pregnancy offers new insights into mechanisms of breast cancer risk and resistance. Breast Cancer Res. 2013 Sep 24;15(5):312.