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Sextuplets: an unusual complication of single embryo transfer
Fertility and sterility
  • L. Mains
  • Ginny L. Ryan, University of Iowa
  • Amy E.T. Sparks, University of Iowa
  • Bradley J. Van Voorhis, University of Iowa
Document Type
Peer Reviewed
Publication Date
NLM Title Abbreviation
Fertil Steril
PubMed ID
DOI of Published Version
OBJECTIVE: To describe an unusual case of a sextuplet gestation after IVF and transfer of a single blastocyst. DESIGN: Case report. SETTING: University-based IVF clinic. PATIENT(S): A 32-year-old female with secondary infertility undergoing IVF-ET. INTERVENTION(S): Transvaginal oocyte retrieval, transfer of a single blastocyst, and multifetal pregnancy reduction. MAIN OUTCOME MEASURE(S): Ultrasound determination of pregnancy viability. RESULT(S): Six intrauterine gestational sacs, each with a fetus having cardiac activity, reduced to a triplet gestation. CONCLUSION(S): Physicians should consider advising patients undergoing IVF-ET to abstain from unprotected intercourse at least 4 days before the anticipated oocyte retrieval. Incomplete aspiration of ovarian follicles is uncommon but not rare and can lead to a higher order multiple pregnancy if recent unprotected intercourse has occurred in this setting.
  • Adult,
  • Counseling,
  • Embryo Transfer,
  • Female,
  • Fertilization in Vitro,
  • Humans,
  • Infertility,
  • Female/etiology/therapy,
  • Multiple Birth Offspring,
  • Oocyte Retrieval/adverse effects,
  • Ovulation Induction/adverse effects,
  • Polycystic Ovary Syndrome/complications/therapy,
  • Practice Guidelines as Topic,
  • Pregnancy,
  • Pregnancy Reduction,
  • Multifetal,
  • Ultrasonography,
  • Prenatal,
  • Unsafe Sex
Published Article/Book Citation

Fertility and sterility, 91:3 (2009) pp.932.e1-932.e2.

Citation Information
L. Mains, Ginny L. Ryan, Amy E.T. Sparks and Bradley J. Van Voorhis. "Sextuplets: an unusual complication of single embryo transfer" Fertility and sterility Vol. 91 Iss. 3 (2009) p. 9320 - 93200 ISSN: 1556-5653
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