A mandatory single blastocyst transfer policy with educational campaign in a United States IVF program reduces multiple gestation rates without sacrificing pregnancy ratesFertility and sterility
NLM Title AbbreviationFertil Steril
DOI of Published Version10.1016/j.fertnstert.2007.03.001
AbstractOBJECTIVE: To reduce the twin rate in our IVF program. DESIGN: A prospective educational study of infertile couples; a retrospective review of IVF outcomes before vs. after mandatory single embryo transfer (mSBT) policy change. SETTING: University-based infertility center. PATIENT(S): One hundred ten of 120 consecutive new infertile couples completed the educational study. Outcomes of all embryo transfers (n = 693) performed 17 months before and 17 months after mSBT were evaluated. INTERVENTION(S): A 1-page educational summary of comparative risks of twins vs. singletons to maternal and child health. MAIN OUTCOME MEASURE(S): Knowledge of twin risks and desired number of embryos transferred before and after education. Pregnancy rates, number of embryos transferred, and multiple-gestation rates before and after mSBT policy. RESULT(S): After education, knowledge of twin risks improved and a significant number of subjects changed their desired outcome to a lower gestational number. There was no change in ongoing pregnancy rates with blastocyst transfer before and after mSBT (63% vs. 58%; NS). Program-wide number of embryos transferred (2.1 +/- 0.6 vs. 1.9 +/- 0.7) and multiple-gestation rates (35% vs. 19%) decreased significantly while pregnancy rates were maintained. CONCLUSION(S): Simple educational materials can improve knowledge of twin pregnancy risks and affect decision making. In high-risk patients, mSBT results in pregnancy rates similar to two-blastocyst transfer, with decreased twin rates.
- Cell Count,
- Embryo Transfer,
- Fertilization in Vitro/legislation & jurisprudence,
- Health Knowledge,
- Patient Education as Topic,
- Patient Satisfaction,
- Pregnancy Rate,
- Multiple/statistics & numerical data,
- United States
Published Article/Book CitationFertility and sterility, 88:2 (2007) pp.354-360.
Citation InformationGinny L. Ryan, Amy E.T. Sparks, C. S. Sipe, Craig H. Syrop, et al.. "A mandatory single blastocyst transfer policy with educational campaign in a United States IVF program reduces multiple gestation rates without sacrificing pregnancy rates" Fertility and sterility Vol. 88 Iss. 2 (2007) p. 354 - 360 ISSN: 1556-5653
Available at: http://works.bepress.com/ginny_ryan/13/