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Acute Toxicity Testing Without Animals: More Scientific and Less of a Gamble
Application of Alternative Methods Collection
  • Gillian R. Langley, British Union for the Abolition of Vivisection
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In this report, we argue specifically that acute toxicity data should not be sought from animal tests. The underlying principle of such tests on rats and mice is that the results can be effectively extrapolated to humans. In fact, after nearly 80 years of use of these tests, the predictivity of rodent data for human acute toxic effects has been disputed but never proven.

Citation Information
Langley, G. (2005). Acute toxicity testing without animals. London, UK: BUAV.