Skip to main content
Article
Synthesis of 1,4-Phenanthrenequinones via Stannic Chloride-Induced Cyclizations
The Journal of Organic Chemistry
  • George A. Kraus, Iowa State University
  • Alex Melekhov, Iowa State University
Document Type
Article
Publication Version
Published Version
Publication Date
2-17-1999
DOI
10.1021/jo981352f
Abstract

Substituted 1,4-phenanthrenequinones such as 1 are useful building blocks for the preparation of novel materials. Katz and others have shown that compounds such as 1 can be transformed into helicenes by DielsAlder reactions.1 Certain 1,4-phenanthrenequinones also have potential as synthetic intermediates for natural products synthesis. Additionally, some naturally occurring 1,4-phenanthrenequinones such as cypripedium (2) are biologically active.2 Kraus and Carpenter have determined that some 1,4-phenanthrenequinones exhibit inhibitory activity in vitro against the equine infectious anemia virus.3

Comments

Reprinted (adapted) with permission from The Journal of Organic Chemistry, 64(5); 1720-1722. Doi: 10.1021/jo981352f. Copyright 1999 American Chemical Society.

Copyright Owner
American Chemical Society
Language
en
File Format
application/pdf
Citation Information
George A. Kraus and Alex Melekhov. "Synthesis of 1,4-Phenanthrenequinones via Stannic Chloride-Induced Cyclizations" The Journal of Organic Chemistry Vol. 64 Iss. 5 (1999) p. 1720 - 1722
Available at: http://works.bepress.com/george_kraus/99/