Reactions of bridgehead halides. A synthesis of modhephene, isomodhephene, and epi-modhepheneThe Journal of Organic Chemistry
Publication VersionPublished Version
AbstractA Synthesis of modhephene has been achieved, the key feature of which is the use of a novel nucleophilic addition/rearrangement reaction to develop the carbon framework. Stereochemical control of the stereogenic center bearing the methyl group was accomplished by variation of the hydrogenation conditions. As a byproduct of this work, we have clarified structural assignments of intermediates from previous syntheses.
Copyright OwnerAmerican Chemical Society
Citation InformationGeorge A. Kraus and Jianmin Shi. "Reactions of bridgehead halides. A synthesis of modhephene, isomodhephene, and epi-modhephene" The Journal of Organic Chemistry Vol. 56 Iss. 13 (1991) p. 4147 - 4151
Available at: http://works.bepress.com/george_kraus/86/